Waa maxay sababta Magnolia looga soosaaray jilif loogu yeero 'xakameeyaha dheefshiidka ee dabiiciga'? Falanqaynta Sayniska ah ee Fara badan{0}Habab Bartilmaameedka

Siraha Ilaalinta Dheefshiidka ee Magnolia Extract

Cilmi-baaris casri ah ayaa daaha ka qaaday in ay ka kooban tahay isku-dhisyo gaar ah sida Magnolia officinalis oo ka soo jeeda jilif dhaqameed Shiinees ah.magnololiyohonokiol. Sidee qaybahani si isku mid ah ugu shaqeeyaan si ay u noqdaan ilaaliyeyaal dabiici ah habka dheefshiidka?

Saddexda Farsamo ee Muhiimka ah ayaa La Sharaxay

Waa maxay sababta ay u nafiso xiidmaha caloosha?

Waxa uu hawlgeliyaa GABA{0}B reseptors si ay u xakameeyaan isku urursiga saxan xiidmaha mindhicirka ee xad dhaafka ah

Wuxuu xannibaa kanaalada kaalshiyamka si loo yareeyo kacsanaanta muruqa mindhicirka (60% hoos u dhaca baaxadda foosha ee vitro)

Sidee bay ula dagaallamaan boogaha?

Waxay joojisaa dheecaanka aysiidhka gastric: Waxay yaraynaysaa H+/K{1}}Dhaqdhaqaaqa ATPase (45% xakamaynta bamka proton)

Waxay kordhisaa ilaalinta xabka caloosha: Waxay kicisaa dheecaanka prostaglandin E2 (kor u kaca 3-5 laab)

Anti -H. ficilka pylori: Waxay carqaladeysaa baayoolojiyada bakteeriyada (82% heerka ciribtirka)

Maxaa ka dhigaya inay nidaamiso microbiota mindhicirka?

Waxay kor u qaadaa korriinka bifidobacterium (kor u kaca 2-3 laab)

Wuxuu joojiyaa cudurada sida C. difficile (15-18mm dhexroor aagga xannibaadda)

Afar Faa'iido oo Kiliinig ahaan La Xaqiijiyay

Dyspepsia shaqaynaysa

68% hoos u dhac ku yimaadda buuxnaanta epigastric

72% horumar ku yimaadda dheregnaanta hore

Cudurka mindhicirka xanaaqa (IBS)

55% hoos u dhaca inta jeer ee xanuunka caloosha

60% hagaajinta joogtada ah ee mindhicirka

Daaweynta Boogaha Caloosha ee Isku-dhafan

40% degdeg ah bogsashada boogaha

50% heerka soo noqoshada hoose

Antibiyootig{0} Shuban la xidhiidha

65% hoos u dhaca dhacdooyinka

50% ka gaaban mindhicirka microbiota wakhtiga soo kabashada

Hagaha Xulashada Sayniska ee Habaynta

Kahortagga Isticmaalka Muhiimka ah

⚠ Yaa la gudboon inay taxaddar muujiyaan?

Haweenka uurka leh (waxa laga yaabaa inay saameeyaan muruqa siman ee ilmo galeenka)

Bukaannada dhiig-karka ah (cadaads dhiig oo khafiif ah{0}saamaynta hoos u dhigista)

⚠ Digniinta Is-dhexgalka Daroogada

Daawooyinka dejin kara ee suurtogalka ah (habaynta qiyaasta ayaa loo baahan yahay)

Waxay saamayn kartaa daawada xinjirowga lidka ku ah (kormeer INR)

Saddex Heerarka Dahabka ah ee Tayada

① Wadarta magnolol+honokiol Ka weyn ama la mid ah 25% (HPLC waa la xaqiijiyay)
② Jilif{0}} laga soo qaatay (5-8× ka firfircoon soosaar caleen)
③ Waxay la kulmaa xadadka farmacopoeia microbial (CFU<100/g)

Marqaatiyada Isticmaalaha

"Sanadahaygii bararka IBS aad bay u fiicnaadeen 2 toddobaad ka dib" - 32shaqaale xafiiska yo
"Xawaaraha bogsashada boogahayga ayaa la yaabay xitaa dhakhtarka gastroenteristka" - 45 yo fulinta

Horumarrada Cilmi-baarista Makaanikada

Xididka -Modulation Brain Axis Modulation(Natiijooyin cusub)

Waxay saamaysaa CNS iyada oo sii marta neerfaha vagus

Waxay yaraysaa dareen-xumada visceral-ka (35% heerka xanuunka oo sarreeya)

Dayactirka Gut Barier(Daraasaadka Xoolaha)

2× korodhka isku xidhka borotiinka ee ZO-1

40% hoos u dhaca heerarka serum endotoxin

Maxaa ka dhigaya Magnolia soo saarista mid gaar ah?
Marka la barbar dhigo hal -daawoyinka bartilmaameedka ah ee GI, magnolia soosaarku waxa uu shaqeeyaa:

- Isku-dhafka qaybaha badan (magnolol + honokiol)

Waxqabad badan - nidaamka (dareemaha + muruqa siman + microbiota)

Nidaaminta labada jiho (dheellitirka hyper/hypo{0}}hawlaha)