Qeexitaanka Alaabta
Iyadoo 2000+ sano ee isticmaalka daawada, markii ugu horeysay la duubayShennong's Classic of Materia Medica. Compendium ee Materia Medicawaxay diiwaangelisaa saamaynta ay ku leedahay "dabaysha{0}} xanuunka qabow, madax-xanuun, garaaca wadnaha, iyo caabuqyada dulin.
Isha Walxaha ceeriin
Goobaha Wax-soo-saarka ugu MuhiimsanSichuan (aagga wax soo saarka saxda ah), Hubei, Shaanxi, Gansu
Heerka Goynta: Premium quality bark from trees aged >15 sano
Xiliga Goynta: Abriil {{0}June (kooxaha ugu firfircoon ee ka kooban)
Qaybaha firfircoon
|
Qayb |
Kala Duwanka Mawduuca |
Faa'iidooyinka aasaasiga ah |
|
Magnolol |
Ka weyn ama la mid ah 10%-98% |
Ka-hortagga bakteeriyada, ka hortagga{0}bararka, suuxinta CNS |
|
Honokool |
Ka weyn ama la mid ah 5% -90% |
Anxiolytic, neuroprotective |
|
Wadarta Phenols |
Ka weyn ama la mid ah 20%-95% |
Dhaqdhaqaaq noole oo dhamaystiran |
|
{{0}Eudesmol |
Ka weyn ama la mid ah 1%-5% |
Nidaaminta caloosha iyo mindhicirka |
|
Saliida Muhiimka ah |
0.5%-2% |
Calool udgoon |
Tilmaamaha Kiimikaad
Muuqashada: Brown -jaal ilaa bunni budo ganaax ah (laga soosaaray heerka caadiga ah)/kiristaalo cad (sare-nadiif)
ur: Udgoon sifada, xoogaa qadhaadh
Solubility:
Si fudud ugu milma ethanol, methanol, acetone
Waxoogaa ku milmay biyo kulul (60 darajo milmi 1.2g/100ml)
Dhab ahaantii aan lagu milmin biyo qabow
Tilmaamaha Alaabta
|
Koodhka badeecada |
Maadada Magnolol |
Waxyaabaha Honokiol |
Baakadaha |
|
MBE-10 |
Ka weyn ama la mid ah 10% |
Ka weyn ama la mid ah 5% |
25kg/durbaan |
|
MBE-30 |
Ka weyn ama la mid ah 30% |
Ka weyn ama la mid ah 15% |
20kg/durbaan |
|
MBE-50 |
Ka weyn ama la mid ah 50% |
Ka weyn ama la mid ah 25% |
10kg/durbaan |
|
MBE-98 |
Ka weyn ama la mid ah 98% |
- |
1kg / bac aluminium ah |
Nolosha Shelf & Kaydinta
Nolosha shelf: 36 bilood (aan la furin)
Xaaladaha Kaydinta:
Heerkulka: 2-8 darajo (dheer{3}}); In ka yar ama la mid ah 25 darajo (muddo gaaban)
Qoyaanka: RH In ka yar ama la mid ah 60%
Iftiin - caddayn, shaabadaysan, qoyaan{1} caddayn
Farsamada Wax-soo-saarka
"Ultrasound{0}}wuxuu caawiyay CO₂ soo saarista sare":
Dawaynta alaabta ceeriin (nadiifinta, 40-mesh shiidi)
Ultrasound{0}ku caawiyay soo saarista (40kHz, 50 darajo)
Sifeynta CO₂ heer sare ah (35MPa, 45 darajo)
Molecular distillation (purity >98%)
Nidaamka Xakamaynta Tayada
Tijaabada Saddex-jeer: HPLC (content), GC-MS (haraaga millatariga), ICP{1}}MS (macno culus)
U Hogaansanaanta Caalamiga ah: USP, EP, JP heerarka
Dufcaddii Raadinta: Raadinta silsiladda sahayda oo buuxda
Falanqaynta Farsamada
Isbarbardhigga Habka Soo Saaridda
|
Habka |
Wax-soo-saarka |
daahirnimo |
Haraaga Solvent |
Isticmaalka Tamarta |
|
Decoction dhaqameed |
8-12% |
In ka yar ama la mid ah 5% |
Midna |
Hoose |
|
Soo saarista ethanol |
15-20% |
10-30% |
In ka yar ama la mid ah 500ppm |
Dhexdhexaad |
|
Heer sare CO₂ |
25-35% |
50-98% |
0ppm |
Sare |
Tilmaamayaasha Tayada Muhiimka ah
Kiimiko kiimikaad:
Qoyaanka In ka yar ama la mid ah 5.0%
Dambas In ka yar ama la mid ah 3.0%
Biraha culus Wax ka yar ama la mid ah wadarta 10ppm
Microbiological:
TAC In ka yar ama la mid ah 1000CFU/g
Caar/khamiir in ka yar ama la mid ah 100CFU/g
E. coli/Salmonella: Negative
Barashada xasilloonida
Tijaabada La Dardargeliyay (40 darajo ± 2 darajo, RH75% ± 5%):
|
Waqtiga (bilo) |
Maadada Magnolol |
Waxyaabaha Honokiol |
|
0 |
100% |
100% |
|
3 |
98.5% |
97.8% |
|
6 |
96.2% |
95.1% |
Faa'iidooyinka Alaabta
Awoodaha Muhiimka ah
1. Faa'iidooyinka Agabka
Sahayda tooska ah ee saldhigga beerashada ee Sichuan GAP
Exclusive use of >15 - jilif premium oo jir ah
Barcoding DNA ee dufcad kasta
2. Faa'iidooyinka Tignoolajiyada
Ultrasound-ka gaarka ah {{0} Farsamada CO₂ aadka u saraysa (Patent: ZL2020XXXXXX)
Nadiifi ilaa 98% (Heerka warshadaha: 20%)
Sawir-fareed dhammaystiran (12 heer sare ah)
3. Faa'iidooyinka Waxtarka
30% saamaynta anxiolytic ka fiican marka loo eego tartamayaasha (baaritaannada xayawaanka)
Balaadhan- spectrum antimicrobial (50% qiimayaasha MIC hoose)
3× ka sareeya helitaanka noolaha (nano{1}}farsamo la xoojiyey)
Codsiyada Alaabta
Daawooyinka
1. Wakiilada Neerfaha
Anxiolytics (benzodiazepine beddelka)
daawaynta adjuvant ee Alzheimers
Hababka ka hortagga niyad-jabka
2. Daawooyinka dheefshiidka
Nidaamiyeyaasha dhaqdhaqaaqa dhaqdhaqaaqa GI
Kahortagga - boogaha
Modulator-ka microbiota gut
Alaabooyinka Caafimaadka
1. Cuntooyinka shaqeeya
Cabbitaannada walaaca ka hortagga{{0}
Hurdada - budada hagaajinta
GI caafimaadka granules
2. Nafaqada
Jilicsanaanta Anxiolytic (100-200mg/maalintii)
Dhismayaasha ilaalinta neerfaha (oo leh Ginkgo)
Xakamaynta niyadda menopause
3. Daryeelka Shakhsi ahaaneed
3.1. Daryeelka afka
Daawada cadayga ee ka hortaga ({0} waxay joojisaa S. mutans)
Boogaha afka
3.2. Daryeelka maqaarka
Daawaynta finanka (ka hortagga- finanka finanka)
Kahortagga - serumyada gabowga
Ka taxadaritaan
Tilmaamaha Isticmaalka
Qiyaasta lagu taliyay:
Cuntooyinka: 0.01-0.1%
Kaabayaasha: 50-200mg maalin kasta
Waxyaabaha la isku qurxiyo: 0.5-2%
Xogta Badbaadada
LD50 ~ 5000mg/kg ( afka jiirka)
Non-mutagenic (Ames tijaabin taban)
Digniinta uurka (xogta badbaadada oo aan ku filnayn)
Baakaynta & Kaydinta
- Xirmooyinka: 1kg/bac bireed, 25kg/ durbaan fiber ah (la beddeli karo)
- Kaydinta: Ku kaydi meel qabow oo qallalan, xidhan oo laga ilaaliyo iftiinka
- Nolosha shelf: 24 bilood (shuruudo aan la furin)
Hal adeeg joogsi
Walxaha ceeriin → budada → Soosaar → Alaabooyinka OEM ee la dhameeyay
Ku badbaadi 20% Qiimaha, Tayada la raadin karo!
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